Mark Distefano

Distinguished McKnight Professor and Distinguished Teaching Professor of Chemistry and Medicinal Chemistry


Email[email protected]

Chemical Biology; Organic Chemistry 

Univ. of Minnesota
Dept. of Chemistry
A-8, 139 Smith Hall
207 Pleasant St. SE
Minneapolis, MN 55455-0431

Office:   668C Kolthoff Hall
Phone:   612-624-0544


B.A.- Biochemistry and Chemistry (1979 - 1984) University of California, Berkeley
Ph.D.- Chemistry (1984 - 1989) Massachusetts Institute of Technology, Cambridge
Postdoc.- Chemistry (1989 - 1992) California Institute of Technology, Pasadena

Employment History

2009 – present Professor Department of Chemistry, University of Minnesota, Minneapolis, MN
1998 – 2009 Associate Professor Department of Chemistry, University of Minnesota, Minneapolis, MN
1992 – 1998 Assistant Professor Department of Chemistry, University of Minnesota, Minneapolis, MN
1989 – 1992 Postdoctoral Fellow, Department of Chemistry, California Institute of Technology, Pasadena, CA
1987 – 1989 Visiting Scientist, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA

Other Appointments

2006 – present Medicinal Chemistry Graduate Program Member
2005 – present Microbial Biotechnology Graduate Program Member
2005 – present University of Minnesota Biotechnology Institute Member
2003 – 2006 Director of Graduate Studies in Chemistry
2001 Visiting Scientist, Genentech Corporation, South San Francisco, CA
1995 – present University of Minnesota Cancer Center Member

Selected Awards

2014 American Chemical Society Fellow
2011 Distinguished McKnight University Professor
2011 Merck Professor of Chemistry
2006 Horace T. Morse-University of Minnesota Distinguished Teaching Professor
2004 George W. Taylor/ITAS Award for Distinguished Teaching
1994 National Science Foundation CAREER Award
1994 American Cancer Society Junior Faculty Research Award
1992 3M Alumni Assistant Professor
1989 Damon Runyon - Walter Winchell Cancer Foundation Fellowship

Professional Organizations

American Chemical Society
American Associate for the Advancement of Science
American Peptide Society

Headshot of Mark Distefano